Biostatistics II : W. Christopher Mathews, M.D., M.S.P.H.; Simon Frost, Ph.D.
Objectives : Scholars will understand and conduct more advanced biostatistical analyses including: ANOVA, multiple linear and logistic regression, survival analysis, and Cox proportional hazards modeling. The scholar will also be familiar with person-time rate analysis with Poisson regression and develop a conceptual understanding of major multivariate methods. Quantitative aspects of decision analysis and cost-effectiveness analysis will be covered. Analysis of survey research data will focus on measures of reliability and validity and on sampling designs.
Course Content:
Topic |
Content |
Analysis of Variance |
1- and 2-way ANOVA |
Correlation and simple linear regression |
Measures of association; concepts and procedures |
Multiple Linear Regression |
Continuous and indicator predictor variables |
Logistic Regression |
Odds ratios, model discrimination and calibration |
Survival Analysis |
Life tables, Kaplan-Meier, log rank tests, Cox proportional hazards model |
Person-Time Rate Analysis |
Poisson regression |
Other multivariable methods |
Factor analysis, discriminant analysis, cluster analysis, MANOVA, CART |
Clinical Decision Analysis |
Setting up and folding back trees, sensitivity analysis, cost-effectiveness analysis |
Analytic methods in survey research
|
Reliability, Validity, Sampling designs |
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